2019-nCoV S-RBD Ikhithi Yokuhlola I-Antibody Neutralizing (indlela yegolide ye-colloidal)
Isingeniso
Njengamanje, yonke imithi yokugoma ka-2019-nCoV ekuthuthukisweni komtholampilo ilawulwa ngomjovo we-intramuscular.Ukugoma nge-intramuscular noma intradermal kungaholela ekungenweni okuqinile kwe-serum IgG
Bangaphezu kuka-180 abantu abazogomela, ngokusekelwe ezisekelweni eziningana ezihlukene okwamanje asathuthuka ngokumelene ne-2019-nCoV.
Iprotheni ye-S iyinkomba eyinhloko yokuqeda amasosha omzimba;
Amaningi alawa amasosha omzimba anciphisa aqondise i-RBD yephrotheni S.
Ungahlulela kanjani ukusebenza kahle komgomo ka-2019-nCoV?--- Ikhithi Yokuhlola I-Antibody Neutralizing
Inzuzo
Ukuhlolwa kokugoma kwangaphambili
Ngaphambi kokugoma, abazobhapathizwa bangakwazi ukubona i-antibody ye-RBD eyenza ukuthi ingasebenzi ukuze kutholakale ukuthi ukugoma kuyadingeka yini;
Imithi yokugoma eminingi ikhaviwe
Ingabona amasosha omzimba akhiqiza imithi eminingi yokugoma emakethe;
Fast and elula
Ukusebenza kulula, akukho ukutholwa kwensimbi edingekayo, imiphumela ingatholakala kungakapheli imizuzu eyi-15.
Umsebenzi wokuhlonza
Ingahlukanisa i-antibody engathathi hlangothi ka-2019-nCoV ekhiqizwe umgomo ka-2019-nCoV noma i-antibody ekhiqizwe ukutheleleka kwe-2019-nCoV yohlobo oluthile lwemigomo, njengomgomo we-Viral vector (Non-Replicating), umgomo we-RNA base kanye nomgomo we-Protein subunit. ;
Ukuhlolwa kwegazi lonke
Ukuhlolwa kwegazi lonke kwenza ukuhlinza kube lula;
Ububanzi besicelo
Ukugoma kwangaphambili
Thola ukuthi ngabe bangenwe yini i-coronavirus entsha nokuthi basadinga yini ukugonywa;
Isikhathi sokugoma
Ukunquma ukuthi ingabe amasosha omzimba amasha angasebenzi akhiqizwa;
Isigaba sekwephuzile sokujova
Ngokwendawo ewubhubhane ka-2019-nCoV, kuphakanyiswa ukuthi kutholwe ubukhona be-antibody engu-2019-nCoV ethatha amandla njalo njalo ezinyangeni ezintathu.
Izingxenye
| Izingxenye | Izithako Eziyinhloko | Ilayisha ubuningi (Ukucaciswa) | ||
| 1 T/Kit | 20 T/Kit | 50 T/Kit | ||
| Ikhadi lokuhlola | Umucu wokuhlola oqukethe igolide eliyi-colloidal elibhalwe ukuthi anti-human IgG antibody, i-colloidal gold ebhalwe ukuthi anti-chicken IgY antibody, 2019-nCoV S-RBD recombinant protein, Chicken IgY antibody | 1 pc | 20 ama-pcs | 50 ama-pcs |
| I-diluent yesampula | 0.01M Isixazululo sebhafa ye-Phosphate, 0.5% Tween-20 | 0.5mL | 5mL | 10mL |
Ukusebenza
| I-reagent ye-Hecin | Ukuhlolwa kwe-Clinical serum virus neutralization | Ingqikithi | |
| Okuhle | Okubi | ||
| Okuhle | Okuhle | 84 | 9 |
| Okubi | Okubi | 8 | 198 |
| Ingqikithi | Ingqikithi | 92 | 207 |
| Ukuzwela komtholampilo | Ukuzwela komtholampilo | 84/92 91.30% (95%CI: 83.58%～96.17%) | |
| Ukucaciswa komtholampilo | Ukucaciswa komtholampilo | 198/207 95.65% (95%CI: 91.91%～97.99%) | |
| Ukunemba | Ukunemba | 282/299 94.31% (95%CI: 91.05%～96.65%) | |
Ukusebenza kwe-Hecin reagent ngokumelene nendlela yokuqhathanisa ku-serum/plasma specimens.
| I-reagent ye-Hecin | Ukuhlolwa kwe-Clinical serum virus neutralization | Ingqikithi | |
| Okuhle | Okubi | ||
| Okuhle | 84 | 8 | 92 |
| Okubi | 8 | 199 | 207 |
| Ingqikithi | 92 | 207 | 299 |
| Ukuzwela komtholampilo | 84/92 91.30% (95%CI: 83.58%～96.17%) | ||
| Ukucaciswa komtholampilo | 199/207 96.14% (95%CI: 92.53%～98.32%) | ||
| Ukunemba | 283/299 94.65% (95%CI: 91.46%～96.91%) | ||
Ukusebenza kwe-Hecin reagent ngokumelene ne-Comparator Method kuzo zonke izibonelo zegazi.
Inqubo Yokuhlola
Isitifiketi Sokubhalisa
I-JT08-1T
I-JT08-5T
I-JT08-50T
